Staphylococcus epidermidis (SEP) is an opportunistic pathogen, and it is one of the most important pathogens in nosocomial infections caused by indwelling biological materials in patients, accounting for 39.00%. Although in vitro experiments have shown that infected bacteria are sensitive to antibiotics, they are difficult to remove in vivo. Staphylococcus epidermidis can form biofilms on the surface of adherent materials in vivo, which is an important cause of infection. Therefore, basic and clinical research on Staphylococcus epidermidis biofilm has once again become a focus of attention. The formation of Staphylococcus epidermidis biofilm contributes to the development of its drug resistance, which is manifested as resistance to a variety of antibacterial drugs.
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